Our Technology

xPloration   Screening Platform

TM

xPloration is an integrated hardware and software platform that enables high dimensional measurement and analysis of genotype, phenotype and cellular functions at the single cell level, millions of cells at a time.

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xPloration finds rare antibodies others can’t. Our B cell screening workflow is optimized for functional measurements of millions of antibody variants within hours. Unlike other processes that screen only a portion of the immune repertoire, xCella’s groundbreaking screening depth captures a near complete coverage of the repertoire, allowing us to discover rare antibodies against challenging targets such as GPCRs and ion channels.

  • Load

    µPores

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    Single cell isolation for massively parallel functional analysis

  • Screen

    hours

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    Assays include IgG expression, cell surface binding, cross-species reactivity, and cellular activation 

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  • Recover

    paired VH/VL sequences

     

    Our precise laser-based method recovers 1000's single cells for deep functional immune repertoire studies. For pooled populations, we can recover up to 100 cells/sec.
     

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Traditional Hybridoma Workflow

xCella Workflow

Partnership

We partner with leading biopharma companies and academic institutions to discover best-in-class antibodies.

©xCella Biosciences®

1440 O’Brien Drive, Suite D

Menlo Park, CA 94025