TECHNOLOGY | xCella Biosciences

Our Technology

xPloration Screening Platform

TM

xPloration is an integrated hardware and software platform that enables high dimensional measurement and analysis of genotype, phenotype and cellular functions at the single cell level, millions of cells at a time.

xPloration finds rare antibodies others can’t. Our B cell screening workflow is optimized for functional measurements of millions of antibody variants within hours. Unlike other processes that screen only a portion of the immune repertoire, xCella’s groundbreaking screening depth captures a near complete coverage of the repertoire, allowing us to discover rare antibodies against challenging targets such as GPCRs and ion channels.

Load
µPores

Single cell isolation for massively parallel functional analysis
Screen
hours

Assays include IgG expression, cell surface binding, cross-species reactivity, and cellular activation
Recover
paired VH/VL sequences

Our precise laser-based method recovers 1000's single cells for deep functional immune repertoire studies. For pooled populations, we can recover up to 100 cells/sec.